Hypoestrogenism , or estrogen deficiency , referring to lower-than-normal estrogen levels, the main sex hormone in women. In general, lower estrogen levels can cause differences in breast, genitals, urinary tract, and skin.
Hypoestrogenism is most commonly found in postmenopausal women, premature ovarian failure, or having amenorrhea; However, it is also associated with hyperprolactinemia and the use of gonadotropin-releasing hormone (GnRH) analogues in the treatment of endometriosis. It is also associated with scoliosis and young women with type 1 diabetes mellitus.
Video Hypoestrogenism
Symptoms
Presentation of low estrogen levels including hot flashes, headaches, inherited libido, and breast atrophy. The reduced bone density causes secondary osteoporosis and altered atrophy as pH changes in the vagina are also associated with hypoestrogenism.
Low estrogen levels can cause dyspareunia and limited genital excitement due to changes in the four layers of the vaginal wall.
Hipoestrogenism is also considered as one of the major risk factors for developing uncomplicated urinary tract infection (UTI) in postmenopausal women who do not use hormone replacement therapy.
Maps Hypoestrogenism
Cause
- Hypogonadotropic hypogonadism such as hyperandrogenism, lactation, certain drugs (eg, androgen/anabolic steroids, progestogens, prolactin release, GnRH analog) , Pituitary/hypothalamic pituitary malfunction, or isolated hypogonadotropic hypogonadism (eg, Kallmann's syndrome, CHARGE syndrome,
> GnRH insensitivity) Hypogonadotropic hypogonadisms such as menopause, premature ovarian failure, certain drugs (eg, aromatase inhibitors, CYP17A1 inhibitors), gonadotropin insensitivity, or congenital errors of steroid metabolism (eg aromatase deficiency, 17-hydroxylase deficiency, 17, 20- lyase, 3-hydroxysteroid dehydrogenase deficiency, and cholesterol side chain cleavage or steroidogenic acute protein deficiency)
Diagnosis
Treatment
Hormone replacement therapy (HRT) with estrogen can be used to treat hypoestrogenism in both premenopausal and postmenopausal women.
See also
- Lack of aromatase
- estrogen insensitivity syndrome
- Excess aromatase syndrome
- Hypogonadism
- Hyperestrogenism
- Hypoandrogenisme
- Hypergonadism
- Hyperandrogenism
References
External links
- Gonadotropin-releasing hormone agonist-induced hypoestrogenism and blood flow in the cerebral artery.
Source of the article : Wikipedia